15 Healthtech Startups in New York Investors Should Watch in 2026

New York is a large and fast-growing healthcare technology hub. The city brings together major hospitals, research centers, tech firms, investors, and healthcare buyers. This mix gives startups access to clinical talent, customers, data, and capital.

For investors, the opportunity is wide. Companies use artificial intelligence, software, medical devices, and data tools to fix problems across healthcare. Recent deals also show strong interest in clinical AI, chronic care, and mental health.

This article highlights 15 healthtech startups in New York that investors should watch. The list includes early- and later-stage companies across different healthcare areas. Funding size matters, but so do market needs, traction, and technology.

Which healthtech startups in New York should investors watch?

“For me, that gut feel comes down to my perspective on a particular market, and a founder’s ability to build an exceptional, enduring business in that market.”
Latif Peracha, Partner at M13

The above investment advice also applies to healthtech startups. The companies below span key healthcare markets. The list includes a mix of early- and later-stage startups across AI, digital health, medtech, data, and care delivery.

They were selected based on recent funding activity, investor backing, and market opportunity. Technology and relevance to major healthcare trends were also considered.

Startup	Focus	Recent funding
TytoCare	Remote examinations	$25M+
Handspring	Youth mental health	$19M Series B
Pearl Health	Medicare care management	$110M
Cadence	Chronic care	$100M Series C
Prosper AI	Healthcare administration	$30M Series A
Fesarius Therapeutics	Wound healing	$20M Series A
Plant Health	Obesity and cardiometabolic care	$15M Series A
Novellia	Patient health data	$18M Series A
Garner Health	Provider quality	$100M Series E
Triomics	Cancer data and AI	$22M Series B
Century Health	Life sciences data	$5M Seed
Nourish	Metabolic health	$100M Series C
Forus	Patient treatment access	$160M Series A
Aidoc	Clinical AI	$150M Series E
Amperos Health	Revenue-cycle management	$16M Series A

Let’s explore in detail each of the above healthtech startups in New York.

1. TytoCare

15 Healthtech Startups in New York Investors Should Watch in 2026 | NYC Business World — Source – prnewswire.com

TytoCare builds tools for remote medical exams. Its system combines software and medical devices so clinicians can examine patients from a distance. The company raised more than $25 million in growth funding in 2026.

For investors, TytoCare offers exposure to digital care beyond simple video visits. It also supports use cases where remote exams reduce travel and improve access.

2. Handspring

Handspring provides virtual mental healthcare for children, young adults, and families. It raised a $19 million Series B round in 2026.

The company operates in a large and growing mental health market. 2023 data shows that 40% of U.S. high school students reported symptoms of depression. Investors should focus on cost per patient, retention, and outcomes. Also check if care can scale without losing quality.

3. Pearl Health

Pearl Health uses AI and software to help providers manage Medicare patients. It focuses on risk management and value-based care. The company raised $110 million in equity and debt in 2026.

“We believe Pearl Health is changing how providers participate in value-based care, simplifying the data and daily workflow so they can spend more of their time and attention on their patients. We are proud to support this team and what they are building as they enter their next stage of growth,” says Vineeta Agarwala, MD, General Partner at Andreessen Horowitz

4. Cadence

Cadence uses AI to support chronic care for older adults. It raised a $100 million Series C round in 2026.

Chronic disease creates steady demand for care. This gives Cadence a large recurring market. Investors should still review outcomes, adoption by health systems, and cost savings.

5. Prosper AI

Prosper AI focuses on healthcare administration. Its platform automates tasks like scheduling, billing, insurance work, and collections. The company raised $30 million in Series A funding.

Healthcare systems spend heavily on administrative work. The industry spends around $1.3 billion on administrative costs tied to prior authorizations. A tool that saves time and improves revenue collection can show clear ROI. That makes the value case easy to understand.

6. Fesarius Therapeutics

Fesarius Therapeutics is one of the healthtech startups in New York exploring new approaches to wound care and reconstructive surgery. Its technology uses hydrogel-based dermal regeneration templates. The company raised $20 million in Series A funding.

This is a more complex investment area. Investors must consider clinical trials, regulatory approval, manufacturing, and commercial rollout.

7. Plant Health

Implant Health uses AI and value-based care to treat obesity and cardiometabolic disease. It raised $15 million in Series A funding.

Obesity care is a large and expanding market. Scott Kahan, an obesity-medicine specialist, describes obesity as “both a major clinical and population-level problem.” This highlights the broad need for effective long-term care.

8. Novellia

Novellia focuses on patient health records and data access. It aims to give patients more control while helping life sciences companies use anonymized data for research.

The company raised $18 million in Series A funding. Key risks include privacy, consent, data quality, and building a strong data network.

9. Garner Health

Garner Health helps patients choose higher-quality providers using data. It raised $100 million in Series E funding.

Patients often lack clear information when choosing care. Garner’s growth depends on adoption by employers and insurers who want better outcomes and lower costs.

10. Triomics

Triomics uses AI to structure complex cancer records into usable data. It raised $22 million in Series B funding.

Cancer care produces large and messy datasets. Turning this into structured data can speed up research and improve clinical decisions. Investors should assess data access and accuracy.

11. Century Health

Century Health builds clinical data tools for life sciences companies. It raised $5 million in seed funding.

This is an early-stage company. Its success depends on customer growth and data quality. It also needs to prove strong demand for real-world healthcare data.

12. Nourish

Nourish combines virtual nutrition care with medical support. It also uses AI to improve metabolic health. The company raised $100 million in Series C funding.

The market is tied to obesity and long-term metabolic disease. Success depends on engagement, insurance coverage, and measurable health outcomes.

13. Forus

Forus raised $160 million in Series A funding, one of the largest rounds among healthtech startups in New York. Its platform connects doctors, pharmacies, payers, and biopharma companies to improve treatment access.

The company sits across multiple parts of healthcare. Growth depends on network scale, customer adoption, and value delivered to each participant.

14. Aidoc

Aidoc builds clinical AI tools that help doctors detect and respond to medical conditions. It raised $150 million in Series E funding.

Clinical AI is a strong but demanding market. A HIMSS and Medscape survey found that 86% of respondents were already using AI in their medical organizations. Investors should look at clinical proof, regulatory approvals, and hospital adoption.

15. Amperos Health

Amperos Health uses AI to reduce insurance claim denials and recover lost revenue for providers. It raised $16 million in Series A funding.

Denied claims are a major cost for providers. Amperos offers a clear ROI story if it can consistently recover revenue and reduce admin work.

Why are healthtech startups in New York attracting investors?

New York combines healthcare, research, and technology in one place. It has major hospitals, universities, investors, and enterprise buyers. Brenton Fargnoli, a New York digital-health founder and healthcare investor, says the city’s talent density and proximity to major healthcare buyers make it easier for startups to “test, sell, and scale real products.”

According to the DHNY New York Healthcare Innovation Report, healthtech startups in New York continue to show strong momentum with significant early-stage and growth capital flow across clinical AI, mental health, and chronic care.

The city also helps startups build networks across insurers, hospitals, employers, and pharma companies. This can speed up early testing and adoption.

Still, healthcare is hard. Sales cycles are long, regulation is strict, and proof takes time. Investors must still evaluate each company on fundamentals.

What should investors look for before investing?

When reviewing healthtech startups in New York, investors should not focus only on funding size. A large round does not guarantee success.

Key questions include:

Is the market large? Does the problem affect many patients or providers?
Who pays? Patient, employer, insurer, hospital, or pharma?
Does it work? Look for clinical or business proof.
What are the regulatory risks? Some products need approval.
What is the moat? Data, tech, patents, or network effects.
Is unit economics strong? Costs, margins, and retention matter.
Can it scale? Beyond New York to national or global markets.
Does the team understand healthcare? Domain knowledge is critical.

The best companies solve problems that already have budgets attached. That makes value easier to prove.

Conclusion

The growing group of healthtech startups in New York gives investors many ways to access healthcare innovation. Recent funding shows strong interest in AI, patient access, and chronic care. Metabolic health, data platforms, and automation also show interest.

But funding is only a signal. Investors should focus on traction, evidence, regulation, margins, and competitive strength. New York offers both large later-stage companies and early startups with high growth potential. Careful due diligence is still the key to finding winners.